We view this company as one of the dominant players in small molecule drug development, and that includes Big Bio and Big Pharma, suggests biotechnology expert John McCamant in The Medical Technology Stock Letter.
Incyte's (INCY) crackerjack medicinal chemistry team continues to show that they can create better and differentiated drug candidates from the competition.
The key near-term driver for INCY is Jakafi growth, and with the increased sales guidance, the company is delivering. The drug's overall profile continues to improve and the recent survival data proves that Jakafi does much more for myelofibrosis patients than just control symptoms.
We expect results from the pivotal Phase III trial for patients with polycythemia vera��nown by the name, RESPONSE��arly next year, which will allow INCY to submit a supplemental new drug application for Jakafi in the first half of 2014.
Top 5 Companies To Invest In Right Now: Keegan Resources Inc(KGN.TO)
Keegan Resources Inc., a natural resource company, engages in the acquisition and exploration of mineral resources in west Ghana, Africa. The company primarily explores for gold ores. It principally owns interests in the Esaase gold property and the Asumura gold property located in south west Ghana. The company was formerly known as Quicksilver Ventures Inc. and changed its name to Keegan Resources Inc. in August 2004. Keegan Resources Inc. was incorporated in 1999 and is based in Vancouver, Canada.
Top 5 Companies To Invest In Right Now: Calmena Energy Services Inc. (CEZ.TO)
Calmena Energy Services Inc., a diversified energy services company, provides well construction services for the exploration and development of oil and gas reserves in Canada, the United States, Latin America, the Middle East, and north Africa. The company�s services include well construction engineering and planning, contract drilling, directional drilling, microseismic, frac fluids management, and equipment rental services, as well as drilling and wireline technology solutions. It also offers project management solutions to its clients; and various commercial applications, including day rate, turnkey, and fixed price projects. The company was formerly known as BlackWatch Energy Services Corp. and changed its name to Calmena Energy Services Inc. in June 2010. Calmena Energy Services Inc. was founded in 2006 and is headquartered in Calgary, Canada.
Arcos Dorados Holdings Inc., incorporated on December 9, 2010, is a McDonald�� franchisee. As of December 31, 2010, the Company operated or franchised 1,755 McDonald��-branded restaurants, which represented 6.7% of McDonald�� total franchised restaurants globally. It operates McDonald��-branded restaurants under two different operating formats, Company-operated restaurants and franchised restaurants. As of December 31, 2010, of its 1,755 McDonald��-branded restaurants in the territories, 1,292 (or 74%) were Company-operated restaurants and 463 (or 26%) were franchised restaurants. It generates revenues from two sources: sales by Company-operated restaurants and revenues from franchised restaurants, which consist of rental income, which is based on the greater of a flat fee or a percentage of sales reported by franchised restaurants. As of December 31, 2010, it owned the land for 510 of its restaurants (totaling approximately 1.2 million square meters) and the buildings for all but 12 of its restaurants. It divides its operations into four geographical divisions: Brazil; the Caribbean division, consisting of Aruba, Curacao, French Guiana, Guadeloupe, Martinique, Puerto Rico and the United States Virgin Islands of St. Croix and St. Thomas; North Latin America division (NOLAD), consisting of Costa Rica, Mexico and Panama, and South Latin America division (SLAD), consisting of Argentina, Chile, Colombia, Ecuador, Peru, Uruguay and Venezuela. As of December 31, 2010, 35.1% of its restaurants were located in Brazil, 29.7% in SLAD, 27.1% in NOLAD and 8.1% in the Caribbean division. The Company conducts its business through its indirect, wholly owned subsidiary Arcos Dorados B.V.
Company-Operated and Franchised Restaurants
The Company operates its McDonald��-branded restaurants under two basic structures: Company-operated restaurants operated by the Company and franchised restaurants operated by franchisees. Under both operating alternatives the real estate location m! ! ay either be owned or leased by the Company. It owns, fully manages and operates the Company-operated restaurants and retains any operating profits generated by such restaurants, after paying operating expenses and the franchise and other fees owed to McDonald�� under the Master Franchise Agreements (MFAs). In Company-operated restaurants, it assumes the capital expenditures for the building and equipment of the restaurant and, if it owns the real estate location, for the land as well. Under its franchise arrangements, franchisees provide a portion of the capital required by initially investing in the equipment, signs, seating and decor of their restaurants, and by reinvesting in the business over time. It is required by the MFAs to own the real estate or to secure long-term leases for franchised restaurant sites. It subsequently leases or subleases the property to franchisees.
In exchange for the lease and services, franchisees pay a monthly rent to the Comp any, based on the greater of a fixed rent or a certain percentage of gross sales. In addition to this monthly rent, it collects the monthly continuing franchise fee, which generally is 5% of the United States dollar equivalent of the restaurant�� gross sales, and pays these fees to McDonald�� pursuant to the MFAs. However, if a franchisee fails to pay its monthly continuing franchise fee, it remains liable for payment in full of these fees to McDonald��. As of December 31, 2010, it was engaged in several joint ventures, which collectively owned 24 restaurants, in Argentina, Chile and Colombia.
Restaurant Categories
The Company classifies its restaurants into one of four categories: freestanding, food court, in-store and mall stores. Freestanding restaurants are the type of restaurant, which have ample indoor seating and include a drive-through area. Food court restaurants are located in malls and consist of a front counter and kitchen and do not have their own seating area. In-store restaurants are! pa! rt o! f a l! arger building and resemble freestanding restaurants, except for the lack of a drive-through area. Mall stores are located in malls like food court restaurants, but have their own seating areas. As of December 31, 2010, 808 (or 46.2%) of its restaurants were freestanding, 359 (or 20.5%) were food court, 265 (or 15.1%) were in-stores and 319 (or 18.2%) were mall stores. In addition, it has four non-traditional stores, such as food carts.
Reimaging
As of December 31, 2010, the Company had completed the reimaging of 308 of 1,569 restaurants. Many of the reimaging projects include the addition of McCafe locations to the restaurant. It has developed system-wide guidelines for the interior and exterior design of reimaged restaurants.
McCafe Locations and Dessert Centers
McCafe locations are stylish, separate areas within restaurants where customers can purchase a range of customizable beverages, including lattes, cappuccinos, mochas, hot and iced premium coffees and hot chocolate. As of December 31, 2010, there were 267 McCafe locations in the Territories, of which 12% were operated by franchisees. Argentina, with 71 locations, has McCafe locations, followed by Brazil, with 67 locations. In addition to McCafe locations, it has Dessert Centers. Dessert Centers operate from existing restaurants, but depend on them for supplies and operational support. As of December 31, 2010, there were 1,306 Dessert Centers in the Territories.
Product Offerings
The Company�� menus feature three tiers of products: affordable entry-level options, such as its Big Pleasures, Small Prices or Combo del Dia (Daily Extra Value Meal) offerings, core menu options, such as the Big Mac, Happy Meal and Quarter Pounder, and premium options, such as Big Tasty or Angus premium hamburgers and chicken sandwiches and low-calorie or low-sodium products, which are marketed through common platforms rather t han as individual items. These platforms can be base! d on the!! type of ! products, such as beef, chicken, salads or desserts, or on the type of customer targeted, such as the children�� menu.
Top 5 Companies To Invest In Right Now: Northwest Natural Gas Company(NWN)
Northwest Natural Gas Company stores and distributes natural gas primarily in Oregon, Washington, and California. The company operates in two segments, Local Gas Distribution and Gas Storage. The Local Gas Distribution segment distributes natural gas in Oregon and southwest Washington. The Local Gas Distribution segment distributes natural gas in Oregon and southwest Washington. This segment engages in building and maintaining pipeline distribution system, purchasing gas from producers and marketers, contracting for the transportation of gas over pipelines from the supply basins to service territory, and reselling the gas to customers. It also transports gas owned by customers from the interstate pipeline connection, or city gate, to the customers? facilities. This segment serves various industries, including pulp, paper, and other forest products; companies manufacturing electronic, electrochemical, and electrometallurgical products; companies engaged in processing of fa rm and food products; metal fabrication and casting companies; organizations that produce various mineral products, machine tools, machinery, and textiles; companies that manufacture asphalt, concrete, and rubber; printing and publishing companies; nurseries; government and educational institutions; and electric generation companies. It has approximately 674,000 utility customers comprising approximately 611,000 residential, 62,000 commercial, and 1,000 industrial customers. The Gas Storage segment offers underground natural gas storage services to interstate and intrastate customers. It holds interests in approximately 9,900 net acres of underground natural gas storage in Oregon and approximately 5,000 net acres of underground natural gas storage in California. This segment serves primarily natural gas distribution, electric generation, and energy marketing companies. The company was founded in 1910 and is headquartered in Portland, Oregon.
Top 5 Companies To Invest In Right Now: Montpelier RE Holdings Ltd (MRH)
Montpelier Re Holdings Ltd., through its subsidiaries, provides insurance and reinsurance solutions worldwide. It provides reinsurance products, including property catastrophe reinsurance, which provides coverage for losses from earthquakes, hurricanes, floods, tornados, fires, and storms; and property specialty reinsurance products. The company also offers other specialty reinsurance products, such as aviation liability, aviation war, engineering, space, marine, personal accident, workers� compensation, political violence, casualty, credit, surety, crop, and other specialty reinsurance products, as well as physicians� treaty and professional liability reinsurance products. In addition, it provides direct insurance and facultative reinsurance coverage on industrial, commercial, and residential property; liability; marine; and space risks, as well as political violence, pandemic and event contingency, and terrorism coverages. The company offers its products through indepe ndent brokers, general agents, and intermediaries. Montpelier Re Holdings Ltd. was founded in 2001 and is headquartered in Pembroke, Bermuda.
Summing up his market calls, Doll (left) on Monday wrote in “A Mid-Year 10 Predictions Assessment” that equities had a strong six-month period despite a May and June correction primarily due to a very difficult bond market.